The face is the part of the body which is most exposed to damage by external factors and air pollution. It is also the place where the effects of problems such as acne and skin ageing are most visible. It is therefore advisable to adopt a proper beauty routine with the right daily skincare products.
Today, there are products – such as detergents, anti-acne products or the classic anti-wrinkle cream – that are suitable for all ages, skin types, phototypes, and any related problems. Notwithstanding the proliferation of innovations that have made the cosmetics industry extremely competitive, one thing always remains the most important: the efficacy of a product is fundamental for consumers and the success of the product itself.
Abich – Lifeanalytics, the Group’s Competence Center for Pharma and Cosmetics industries, offers the full range of tests necessary to ensure the safety and efficacy of your skincare products, thus guaranteeing results with high clinical-cosmetological value.
Find out the full range of tests:
The test is designed to be applied to visage and body cosmetics for oily skin with the purpose of substantiating claims “Non-comedogenic” and “Seboregulating” according to Guidelines to Commission Regulation (EU) No 655/2013.
Sebometric measurements in triplicate performed with Sebometer® at T=0 and T=X days after the treatment. Measurements will be performed on the cheeks after treatment. The untreated forehead will be used as a control. The measurements will compensate for circadian rhythms and will therefore be performed at the same time during the day. Open and closed comedones will be counted under Wood’s lamp illumination. Clinical evaluation of high resolution imaging will be performed using a contrast system at T=0 and after X days of treatment.
The test is designed to cosmetics and raw cosmetic ingredients with the purpose of substantiating the claim “Anti-acne” according to proprietary method.
Evaluation of the anti-acne efficacy by testing the inhibition of the proliferation of Propionibacterium acnes by an ingredient or finished product
The test is designed to active ingredients or finished products with the purpose of substantiating the claim “Seboregulating” according to proprietary method.
Quantification of the changes in the gene expression of 5α-reductase in human dermal papilla cells. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II.
The test is designed to active ingredients or finished products with the purpose of substantiating the claim “Seboregulating” according to proprietary method.
Quantification of the changes in the gene expression of 5α-reductase in murine Balb/3T3 fibroblasts. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II.
The test is designed to active ingredients or finished products with the purpose of substantiating the claim “Seboregulating” according to proprietary method.
Analysis of the in vitro expression of the 5α-reductase enzyme by real time PCR in comparison with untreated substrates for the evaluation of inhibition effects. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II.
The test is designed to active ingredients or finished products with the purpose of substantiating the claim “Seboregulating” according to proprietary method.
Analysis of the activation of the activity of enzymatic lipase in a controlled triglyceride hydrolysis reaction.
The test is designed to raw materials and finished products with the purpose of substantiating claims “Anti-aging” and “Reduces signs of aging” according to proprietary method.
In vitro evaluation of the synthesis of hyaluronic acid up to 48h following exposure to the sample, in several concentrations, on skin and dermal papillae fibroblasts.
The test is designed to substances or mixtures with the purpose of substantiating claims “No skin sensitizing” and “Hypoallergenic” according to OECD 442D.
The ARE-Nrf2 method employs cytofluorometry to quantify the antioxidant response in a culture of human keratinocytes after exposure to the product.
The test is designed to raw materials and finished products with the purpose of substantiating claims “Anti-pollution” and “Antioxidant” according to proprietary method.
In vitro test for the evaluation of the protective effect against air pollution. The purpose of this test is to evaluate the efficacy of the sample in reducing ROS release in response to a mix of heavy metals and atmospheric dust particulate in a skin-derived cell model.
The test is designed to raw materials with the purpose of substantiating the claim “Antioxidant” according to UE Regulations.
Quantification of the antioxidant efficacy through ORAC (Oxygen Radical Absorbance Capacity) test.
The test is designed to visage products for mature skin with the purpose of substantiating claims “Anti-aging”, “Reduces signs of aging” and “Illuminating” according to Guidelines to Commission Regulation (EU) No 655/2013.
Instrumental evaluation of R0, R2 and R9 parameters. Instrument: MPA580 Cutometer® for the determination of skin viscoelasticity. Manufacturer: Courage-Khazaka GmbH (Germany).
The L* parameter is also quantified for skin brightness. The effect is quantified through reflection colorimetry using a CL-200 Chromameter Measurements of parameters L* and b* are performed before and after the application of the product.
The test is designed to finished products and substances with the purpose of substantiating the claim “Antioxidant” according to proprietary method.
Colorimetric evaluation of the antioxidant activity of the sample in solution on a controlled oxidation reaction. Results in terms of percentage of decrease of oxidation processes caused by free oxygen radicals.
The test is designed to raw ingredients or finished products with the purpose of substantiating the claim “Antioxidant” according to proprietary method.
Quantification of the efficacy of the sample in inhibiting cytoplasmic oxidation phenomenon and protecting the skin cell model (immortalized human keratinocytes) from damaged caused by ROS.
The test is designed to finished products and active ingredients with the purpose of substantiating claims “Anti-aging” and “Redensifies and tones the epidermis” according to proprietary method.
Quantitative evaluation of the efficacy of a product or active ingredient in increasing cell proliferation and protein synthesis. MTT test and protein quantification at different time intervals. The test can be performed on human keratinocytes or fibroblasts.
The test is designed to raw materials and finished products with the purpose of substantiating the claim “Inhibition of bacterial adhesion” according to proprietary method.
Evaluation of bacterial adhesion on mammal cells, performed on the CACO-2 cell line.
The test is designed to be applied to chemical substances or mixtures with the purpose of substantiating the claim “Non-irritant for the eyes” according to OECD 492.
Identification of chemical substances or mixtures that do not require classification as (severe) irritants through evaluation of their cytotoxic effects on an in vitro reconstructed corneal epithelium model.
NOTE: if the sample qualifies as irritant, further tests are required in order to determine the degree of irritant action.
The test is designed to be applied to raw ingredients or finished products with the purpose of substantiating the claim “Non-irritant for the eyes (CLP Labeling)” according to OECD 491.
Short term exposure analysis by application of each tested substance on SIRC (Statens Seruminstitut Rabbit Cornea) cells for the determination of the effect on cell viability through MTT test.
The test is designed to be applied to chemical substances or mixtures with the purpose of substantiating the claim “Non-irritant for the skin” according to OECD 439.
Patch test for the evaluation of the irritation potential of chemical substances or mixtures through evaluation of their cytotoxic effect on an in vitro reconstructed model of human skin.
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